Elizabeth Jasicki splendidly narrates P53 The Gene That Cracked The Cancer Code. This amazing book was written by Sue Armstrong. I’m always awe inspired when science is explained in an accessible way to people who, like me, don’t have the greatest science aptitude but have an avid interest.
P53 is the gene that protects us from cancer. Through the efforts of indomitable scientists, P53’s pivotal role in determining who will be ravaged by cancer and who will not has been repeatedly affirmed. One scientist purposely radiated his arm with a sun light to show that UV rays generate cell growth. If P53 is mutated, skin cancer can readily develop. Scientists have discovered two factors pertaining to skin cancer:
1) A serious sun burn in childhood;and;
2) Unprotected exposure to the sun in adulthood.
This was supported by ascertaining that light skin individuals who immigrate to areas with high sun exposure have a lower skin cancer rate than light skin individuals who have spent their entire lives in these areas.
With smoking and lung cancer, the evidence at first appeared circumstantial until tobacco’s mutating effect on P53 was conclusively proven. Some tobacco companies employed their own scientists and although they tried to discredit the link between smoking and cancer, the evidence became unassailable.
At its heart, P53 The Gene That Cracked The Cancer Code, is a story of dedicated sleuthing by the scientific community that led to a greater understanding of a disease that you can’t get through life without being impacted by in some way — either through your own experience or a family member or friend. If you could give more than five stars to a reviewed book, I’d give ten to this one.
Disclosure: I received a copy from Audible in exchange for an honest review.